Cargando…

Zinc metalloproteinase ZmpC suppresses experimental pneumococcal meningitis by inhibiting bacterial invasion of central nervous systems

Streptococcus pneumoniae is a leading cause of bacterial meningitis. Here, we investigated whether pneumococcal paralogous zinc metalloproteases contribute to meningitis onset. Findings of codon-based phylogenetic analyses indicated 3 major clusters in the Zmp family; ZmpA, ZmpC, and ZmpB, with ZmpD...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamaguchi, Masaya, Nakata, Masanobu, Sumioka, Ryuichi, Hirose, Yujiro, Wada, Satoshi, Akeda, Yukihiro, Sumitomo, Tomoko, Kawabata, Shigetada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810488/
https://www.ncbi.nlm.nih.gov/pubmed/28489958
http://dx.doi.org/10.1080/21505594.2017.1328333