Orexin/hypocretin levels in the cerebrospinal fluid and characteristics of patients with myotonic dystrophy type 1 with excessive daytime sleepiness

PURPOSE: Myotonic dystrophy type 1 (DM1) is often characterized by excessive daytime sleepiness (EDS) and sleep-onset rapid eye movement periods caused by muscleblind-like protein 2. The EDS tends to persist even after treatment of sleep apnea. We measured the cerebrospinal fluid (CSF) orexin levels...

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Detalles Bibliográficos
Autores principales: Omori, Yuki, Kanbayashi, Takashi, Imanishi, Aya, Tsutsui, Ko, Sagawa, Yohei, Kikuchi, Yuka S, Takeshima, Masahiro, Yoshizawa, Kazuhisa, Uemura, Sachiko, Shimizu, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810517/
https://www.ncbi.nlm.nih.gov/pubmed/29445282
http://dx.doi.org/10.2147/NDT.S158651

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