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Generation of an arrayed CRISPR-Cas9 library targeting epigenetic regulators: from high-content screens to in vivo assays

The CRISPR-Cas9 system has revolutionized genome engineering, allowing precise modification of DNA in various organisms. The most popular method for conducting CRISPR-based functional screens involves the use of pooled lentiviral libraries in selection screens coupled with next-generation sequencing...

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Detalles Bibliográficos
Autores principales:	Henser-Brownhill, Tristan, Monserrat, Josep, Scaffidi, Paola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810758/ https://www.ncbi.nlm.nih.gov/pubmed/29327641 http://dx.doi.org/10.1080/15592294.2017.1395121

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