Transcription factors orchestrate dynamic interplay between genome topology and gene regulation during cell reprogramming

Chromosomal architecture is known to influence gene expression, yet its role in controlling cell fate remains poorly understood. Reprogramming of somatic cells into pluripotent stem cells by the transcription factors (TFs) Oct4, Sox2, Klf4 and Myc offers an opportunity to address this question but i...

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Detalles Bibliográficos
Autores principales: Stadhouders, Ralph, Vidal, Enrique, Serra, François, Di Stefano, Bruno, Le Dily, François, Quilez, Javier, Gomez, Antonio, Collombet, Samuel, Berenguer, Clara, Cuartero, Yasmina, Hecht, Jochen, Filion, Guillaume J., Beato, Miguel, Marti-Renom, Marc A., Graf, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810905/
https://www.ncbi.nlm.nih.gov/pubmed/29335546
http://dx.doi.org/10.1038/s41588-017-0030-7

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