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Bile acid detoxifying enzymes limit susceptibility to liver fibrosis in female SHRSP5/Dmcr rats fed with a high-fat-cholesterol diet

During middle age, women are less susceptible to nonalcoholic steatohepatitis (NASH) than men. Thus, we investigated the underlying molecular mechanisms behind these sexual differences using an established rat model of NASH. Mature female and male stroke-prone spontaneously hypertensive 5/Dmcr rats...

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Detalles Bibliográficos
Autores principales:	Yetti, Husna, Naito, Hisao, Yuan, Yuan, Jia, Xiaofang, Hayashi, Yumi, Tamada, Hazuki, Kitamori, Kazuya, Ikeda, Katsumi, Yamori, Yukio, Nakajima, Tamie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811017/ https://www.ncbi.nlm.nih.gov/pubmed/29438418 http://dx.doi.org/10.1371/journal.pone.0192863

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