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Monitoring tumor response to the vascular disrupting agent CKD-516 in a rabbit VX2 intramuscular tumor model using PET/MRI: Simultaneous evaluation of vascular and metabolic parameters

OBJECTIVES: To determine whether the CKD-516 produces a significant change in vascular and metabolic parameters in PET/MRI MATERIALS AND METHODS: With institutional Animal Care and Use Committee approval, 18 VX2 carcinoma tumors implanted in bilateral back muscles of 9 rabbits were evaluated. Serial...

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Detalles Bibliográficos
Autores principales: Ahn, Su Yeon, Goo, Jin Mo, Lee, Kyung Hee, Ha, Seunggyun, Paeng, Jin Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811032/
https://www.ncbi.nlm.nih.gov/pubmed/29438381
http://dx.doi.org/10.1371/journal.pone.0192706