Cargando…

A hydrogel biosensor for high selective and sensitive detection of amyloid-beta oligomers

BACKGROUND: Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive cognitive and memory impairment. It is the most common neurological disease that causes dementia. Soluble amyloid-beta oligomers (AβO) in blood or cerebrospinal fluid (CSF) are the pathogenic biomarker...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Liping, Zhong, Yong, Gui, Jie, Wang, Xianwu, Zhuang, Xiaorong, Weng, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811178/ https://www.ncbi.nlm.nih.gov/pubmed/29467574 http://dx.doi.org/10.2147/IJN.S152163

Ejemplares similares

A sensitive and selective electrochemical biosensor for the determination of beta-amyloid oligomer by inhibiting the peptide-triggered in situ assembly of silver nanoparticles
por: Xing, Yun, et al.
Publicado: (2017)

Immunogenic properties of amyloid beta oligomers
por: Dalgediene, Indre, et al.
Publicado: (2013)

Sleep is bi-directionally modified by amyloid beta oligomers
por: Özcan, Güliz Gürel, et al.
Publicado: (2020)

Plasma amyloid-beta oligomer is related to subjective cognitive decline and brain amyloid status
por: Kim, Keun You, et al.
Publicado: (2022)

A Rationally Designed Humanized Antibody Selective for Amyloid Beta Oligomers in Alzheimer’s Disease
por: Gibbs, Ebrima, et al.
Publicado: (2019)

Application of an Amyloid Beta Oligomer Standard in the sFIDA Assay
por: Kühbach, Katja, et al.
Publicado: (2016)

Synaptic dysregulation and hyperexcitability induced by intracellular amyloid beta oligomers
por: Fernandez‐Perez, Eduardo J., et al.
Publicado: (2021)

Editorial: Beta-Amyloid oligomer specific treatments for Alzheimer's disease
por: Hillen, Heinz
Publicado: (2023)

Selected microRNAs Increase Synaptic Resilience to the Damaging Binding of the Alzheimer’s Disease Amyloid Beta Oligomers
por: Zolochevska, Olga, et al.
Publicado: (2020)

Beta amyloid oligomers and fibrils stimulate differential activation of primary microglia
por: Sondag, Cindy M, et al.
Publicado: (2009)

Quantitative analysis of co-oligomer formation by amyloid-beta peptide isoforms
por: Iljina, Marija, et al.
Publicado: (2016)

Near infrared light decreases synaptic vulnerability to amyloid beta oligomers
por: Comerota, Michele M., et al.
Publicado: (2017)

Corrigendum: Synaptic dysregulation and hyperexcitability induced by intracellular amyloid beta oligomers
Publicado: (2021)

Flexible nanopillar-based immunoelectrochemical biosensor for noninvasive detection of Amyloid beta
por: Park, Yoo Min, et al.
Publicado: (2020)

Single Molecule Characterization of Amyloid Oligomers
por: Yang, Jie, et al.
Publicado: (2021)

Alzheimer’s disease pathology propagation by exosomes containing toxic amyloid-beta oligomers
por: Sardar Sinha, Maitrayee, et al.
Publicado: (2018)

Stabilization, Characterization, and Selective Removal of Cystatin C Amyloid Oligomers
por: Östner, Gustav, et al.
Publicado: (2013)

The Toxicity of Amyloid β Oligomers
por: Zhao, Li Na, et al.
Publicado: (2012)

Amyloid Self-Assembly of Lysozyme in Self-Crowded Conditions: The Formation of a Protein Oligomer Hydrogel
por: Catalini, Sara, et al.
Publicado: (2021)

An Aged Canid with Behavioral Deficits Exhibits Blood and Cerebrospinal Fluid Amyloid Beta Oligomers
por: Rusbridge, Clare, et al.
Publicado: (2018)

Amyloid Beta Oligomers Target to Extracellular and Intracellular Neuronal Synaptic Proteins in Alzheimer's Disease
por: Ding, Yu, et al.
Publicado: (2019)

Role of Lipocalin-2 in Amyloid-Beta Oligomer-Induced Mouse Model of Alzheimer’s Disease
por: Kang, Heeyoung, et al.
Publicado: (2021)

Plasma amyloid-beta oligomer and phosphorylated tau: diagnostic tools for progressive Alzheimer’s disease
por: An, Seong Soo A., et al.
Publicado: (2023)

Liquid–liquid phase separation of amyloid-β oligomers modulates amyloid fibrils formation
por: Gui, Xinrui, et al.
Publicado: (2023)

An N-terminal antibody promotes the transformation of amyloid fibrils into oligomers and enhances the neurotoxicity of amyloid-beta: the dust-raising effect
por: Liu, Yu-Hui, et al.
Publicado: (2015)

Natural Amyloid-Beta Oligomers Acutely Impair the Formation of a Contextual Fear Memory in Mice
por: Kittelberger, Kara A., et al.
Publicado: (2012)

The culprit behind amyloid beta peptide related neurotoxicity in Alzheimer's disease: oligomer size or conformation?
por: Broersen, Kerensa, et al.
Publicado: (2010)

Beta‐amyloid 1‐42 monomers, but not oligomers, produce PHF‐like conformation of Tau protein
por: Manassero, Giusi, et al.
Publicado: (2016)

Mangiferin and Morin Attenuate Oxidative Stress, Mitochondrial Dysfunction, and Neurocytotoxicity, Induced by Amyloid Beta Oligomers
por: Alberdi, Elena, et al.
Publicado: (2018)

Breaking the Code of Amyloid-β Oligomers
por: Lesné, Sylvain E.
Publicado: (2013)

The Toxicity and Polymorphism of β-Amyloid Oligomers
por: Huang, Ya-ru, et al.
Publicado: (2020)

Molecular interactions between monoclonal oligomer-specific antibody 5E3 and its amyloid beta cognates
por: Khorvash, Massih, et al.
Publicado: (2020)

Amyloid Beta Oligomers-Induced Ca(2+) Entry Pathways: Role of Neuronal Networks, NMDA Receptors and Amyloid Channel Formation
por: Caballero, Erica, et al.
Publicado: (2022)

Kinetic Transition in Amyloid Assembly as a Screening Assay for Oligomer-Selective Dyes
por: Barton, Jeremy, et al.
Publicado: (2019)

Correction: A glycine zipper motif mediates the formation of toxic beta-amyloid oligomers in vitro and in vivo
por: Fonte, Virginia, et al.
Publicado: (2014)

Construction of human Fab library and screening of a single-domain antibody of amyloid-beta 42 oligomers
por: Yuan, Zuanning, et al.
Publicado: (2013)

Multivariate Analyses of Amyloid-Beta Oligomer Populations Indicate a Connection between Pore Formation and Cytotoxicity
por: Prangkio, Panchika, et al.
Publicado: (2012)

Structural Optimization of Foldamer-Dendrimer Conjugates as Multivalent Agents against the Toxic Effects of Amyloid Beta Oligomers
por: Bartus, Éva, et al.
Publicado: (2018)

Alzheimer's Therapeutics Targeting Amyloid Beta 1–42 Oligomers II: Sigma-2/PGRMC1 Receptors Mediate Abeta 42 Oligomer Binding and Synaptotoxicity
por: Izzo, Nicholas J., et al.
Publicado: (2014)

Shared amyloid oligomer structure proves toxic
por: Tuma, Rabiya S.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_e6gjje9181njqt18phf9aj17qf