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Cleavage activates Dispatched for Sonic Hedgehog ligand release

Hedgehog ligands activate an evolutionarily conserved signaling pathway that provides instructional cues during tissue morphogenesis, and when corrupted, contributes to developmental disorders and cancer. The transmembrane protein Dispatched is an essential component of the machinery that deploys He...

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Detalles Bibliográficos
Autores principales:	Stewart, Daniel P, Marada, Suresh, Bodeen, William J, Truong, Ashley, Sakurada, Sadie Miki, Pandit, Tanushree, Pruett-Miller, Shondra M, Ogden, Stacey K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811216/ https://www.ncbi.nlm.nih.gov/pubmed/29359685 http://dx.doi.org/10.7554/eLife.31678

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