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Effects of senescence and angiotensin II on expression and processing of amyloid precursor protein in human cerebral microvascular endothelial cells

The present study was designed to determine the effects of senescence and angiotensin II (Ang II) on expression and processing of amyloid precursor protein (APP) in human brain microvascular endothelial cells (BMECs). Senescence caused a decrease in APP expression thereby resulting in reduced secret...

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Detalles Bibliográficos
Autores principales: Sun, Ruohan, He, Tongrong, Pan, Yujun, Katusic, Zvonimir S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811245/
https://www.ncbi.nlm.nih.gov/pubmed/29348391
http://dx.doi.org/10.18632/aging.101362