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Rapamycin prevents the intervertebral disc degeneration via inhibiting differentiation and senescence of annulus fibrosus cells

The effects of bleomycin and rapamycin on cellular senescence and differentiation of rabbit annulus fibrosus stem cells (AFSCs) were investigated using a cell culture model. The results showed that bleomycin induced cellular senescence in AFSCs as evidenced by senescence-associated secretory phenoty...

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Detalles Bibliográficos
Autores principales:	Gao, Changhong, Ning, Bin, Sang, Chenglin, Zhang, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811247/ https://www.ncbi.nlm.nih.gov/pubmed/29348392 http://dx.doi.org/10.18632/aging.101364

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