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Socioeconomic Inequalities in the Kidney Transplantation Process: A Registry-Based Study in Sweden

BACKGROUND: Few studies have examined the association between individual-level socioeconomic status and access to kidney transplantation. This study aims to investigate the association between predialysis income and education, and access to (i) the kidney waitlist (first listing), and (ii) kidney tr...

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Autores principales: Zhang, Ye, Gerdtham, Ulf-G., Rydell, Helena, Jarl, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811275/
https://www.ncbi.nlm.nih.gov/pubmed/29464207
http://dx.doi.org/10.1097/TXD.0000000000000764
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author Zhang, Ye
Gerdtham, Ulf-G.
Rydell, Helena
Jarl, Johan
author_facet Zhang, Ye
Gerdtham, Ulf-G.
Rydell, Helena
Jarl, Johan
author_sort Zhang, Ye
collection PubMed
description BACKGROUND: Few studies have examined the association between individual-level socioeconomic status and access to kidney transplantation. This study aims to investigate the association between predialysis income and education, and access to (i) the kidney waitlist (first listing), and (ii) kidney transplantation conditional on waitlist placement. Adjustment will be made for a number of medical and nonmedical factors. METHODS: The Swedish Renal Register was linked to national registers for adult patients in Sweden who started dialysis during 1995 to 2013. We employed Cox proportional hazards models. RESULTS: Nineteen per cent of patients were placed on the waitlist. Once on the waitlist, 80% received kidney transplantation. After adjusting for covariates, patients in the highest income quintile were found to have higher access to both the waitlist (hazard ratio [HR], 1.73; 95% confidence interval [CI], 1.53-1.96) and kidney transplantation (HR, 1.33; 95% CI, 1.16-1.53) compared with patients in the lowest income quintile. Patients with higher education also had better access to the waitlist and kidney transplantation (HR, 2.16; 95% CI, 1.94-2.40; and HR, 1.16; 95% CI, 1.03-1.30, respectively) compared with patients with mandatory education. CONCLUSIONS: Socioeconomic status-related inequalities exist with regard to both access to the waitlist, and kidney transplantation conditional on listing. However, the former inequality is substantially larger and is therefore expected to contribute more to societal inequalities. Further studies are needed to explore the potential mechanisms and strategies to reduce these inequalities.
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spelling pubmed-58112752018-02-20 Socioeconomic Inequalities in the Kidney Transplantation Process: A Registry-Based Study in Sweden Zhang, Ye Gerdtham, Ulf-G. Rydell, Helena Jarl, Johan Transplant Direct Kidney Transplantation BACKGROUND: Few studies have examined the association between individual-level socioeconomic status and access to kidney transplantation. This study aims to investigate the association between predialysis income and education, and access to (i) the kidney waitlist (first listing), and (ii) kidney transplantation conditional on waitlist placement. Adjustment will be made for a number of medical and nonmedical factors. METHODS: The Swedish Renal Register was linked to national registers for adult patients in Sweden who started dialysis during 1995 to 2013. We employed Cox proportional hazards models. RESULTS: Nineteen per cent of patients were placed on the waitlist. Once on the waitlist, 80% received kidney transplantation. After adjusting for covariates, patients in the highest income quintile were found to have higher access to both the waitlist (hazard ratio [HR], 1.73; 95% confidence interval [CI], 1.53-1.96) and kidney transplantation (HR, 1.33; 95% CI, 1.16-1.53) compared with patients in the lowest income quintile. Patients with higher education also had better access to the waitlist and kidney transplantation (HR, 2.16; 95% CI, 1.94-2.40; and HR, 1.16; 95% CI, 1.03-1.30, respectively) compared with patients with mandatory education. CONCLUSIONS: Socioeconomic status-related inequalities exist with regard to both access to the waitlist, and kidney transplantation conditional on listing. However, the former inequality is substantially larger and is therefore expected to contribute more to societal inequalities. Further studies are needed to explore the potential mechanisms and strategies to reduce these inequalities. Lippincott Williams & Wilkins 2018-01-24 /pmc/articles/PMC5811275/ /pubmed/29464207 http://dx.doi.org/10.1097/TXD.0000000000000764 Text en Copyright © 2018 The Author(s). Transplantation Direct. Published by Wolters Kluwer Health, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Kidney Transplantation
Zhang, Ye
Gerdtham, Ulf-G.
Rydell, Helena
Jarl, Johan
Socioeconomic Inequalities in the Kidney Transplantation Process: A Registry-Based Study in Sweden
title Socioeconomic Inequalities in the Kidney Transplantation Process: A Registry-Based Study in Sweden
title_full Socioeconomic Inequalities in the Kidney Transplantation Process: A Registry-Based Study in Sweden
title_fullStr Socioeconomic Inequalities in the Kidney Transplantation Process: A Registry-Based Study in Sweden
title_full_unstemmed Socioeconomic Inequalities in the Kidney Transplantation Process: A Registry-Based Study in Sweden
title_short Socioeconomic Inequalities in the Kidney Transplantation Process: A Registry-Based Study in Sweden
title_sort socioeconomic inequalities in the kidney transplantation process: a registry-based study in sweden
topic Kidney Transplantation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811275/
https://www.ncbi.nlm.nih.gov/pubmed/29464207
http://dx.doi.org/10.1097/TXD.0000000000000764
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