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Structural properties of apolipoprotein A-I mimetic peptides that promote ABCA1-dependent cholesterol efflux
Peptides mimicking the major protein of highdensity lipoprotein (HDL), apolipoprotein A-I (apoA-I), are promising therapeutics for cardiovascular diseases. Similar to apoA-I, their atheroprotective property is attributed to their ability to form discoidal HDL-like particles by extracting cellular ch...
Autores principales: | Islam, Rafique M., Pourmousa, Mohsen, Sviridov, Denis, Gordon, Scott M., Neufeld, Edward B., Freeman, Lita A., Perrin, B. Scott, Pastor, Richard W., Remaley, Alan T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811490/ https://www.ncbi.nlm.nih.gov/pubmed/29440748 http://dx.doi.org/10.1038/s41598-018-20965-2 |
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