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Nanobody-triggered lockdown of VSRs reveals ligand reloading in the Golgi
Protein degradation in lytic compartments is crucial for eukaryotic cells. At the heart of this process, vacuolar sorting receptors (VSRs) bind soluble hydrolases in the secretory pathway and release them into the vacuolar route. Sorting efficiency is suggested to result from receptor recycling. How...
Autores principales: | Früholz, Simone, Fäßler, Florian, Kolukisaoglu, Üner, Pimpl, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811495/ https://www.ncbi.nlm.nih.gov/pubmed/29440677 http://dx.doi.org/10.1038/s41467-018-02909-6 |
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