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Nanobody-triggered lockdown of VSRs reveals ligand reloading in the Golgi

Protein degradation in lytic compartments is crucial for eukaryotic cells. At the heart of this process, vacuolar sorting receptors (VSRs) bind soluble hydrolases in the secretory pathway and release them into the vacuolar route. Sorting efficiency is suggested to result from receptor recycling. How...

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Detalles Bibliográficos
Autores principales: Früholz, Simone, Fäßler, Florian, Kolukisaoglu, Üner, Pimpl, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811495/
https://www.ncbi.nlm.nih.gov/pubmed/29440677
http://dx.doi.org/10.1038/s41467-018-02909-6

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