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The effects of death and post-mortem cold ischemia on human tissue transcriptomes

Post-mortem tissues samples are a key resource for investigating patterns of gene expression. However, the processes triggered by death and the post-mortem interval (PMI) can significantly alter physiologically normal RNA levels. We investigate the impact of PMI on gene expression using data from mu...

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Detalles Bibliográficos
Autores principales: Ferreira, Pedro G., Muñoz-Aguirre, Manuel, Reverter, Ferran, Sá Godinho, Caio P., Sousa, Abel, Amadoz, Alicia, Sodaei, Reza, Hidalgo, Marta R., Pervouchine, Dmitri, Carbonell-Caballero, Jose, Nurtdinov, Ramil, Breschi, Alessandra, Amador, Raziel, Oliveira, Patrícia, Çubuk, Cankut, Curado, João, Aguet, François, Oliveira, Carla, Dopazo, Joaquin, Sammeth, Michael, Ardlie, Kristin G., Guigó, Roderic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811508/
https://www.ncbi.nlm.nih.gov/pubmed/29440659
http://dx.doi.org/10.1038/s41467-017-02772-x

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