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Latent Impulsivity Subtypes in Substance Use Disorders and Interactions with Internalizing and Externalizing Co-Occurring Disorders

This study explored the clinical importance of latent impulsivity subtypes within a sample of individuals with substance use disorders (SUDs) and high rates of co-occurring disorders (CODs) receiving residential treatment, aiming to assess the heterogeneity of the associations between SUDs and CODs...

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Autores principales: Marín-Navarrete, Rodrigo, Toledo-Fernández, Aldebarán, Villalobos-Gallegos, Luis, Roncero, Carlos, Szerman, Nestor, Medina-Mora, María Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811514/
https://www.ncbi.nlm.nih.gov/pubmed/29479323
http://dx.doi.org/10.3389/fpsyt.2018.00027
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author Marín-Navarrete, Rodrigo
Toledo-Fernández, Aldebarán
Villalobos-Gallegos, Luis
Roncero, Carlos
Szerman, Nestor
Medina-Mora, María Elena
author_facet Marín-Navarrete, Rodrigo
Toledo-Fernández, Aldebarán
Villalobos-Gallegos, Luis
Roncero, Carlos
Szerman, Nestor
Medina-Mora, María Elena
author_sort Marín-Navarrete, Rodrigo
collection PubMed
description This study explored the clinical importance of latent impulsivity subtypes within a sample of individuals with substance use disorders (SUDs) and high rates of co-occurring disorders (CODs) receiving residential treatment, aiming to assess the heterogeneity of the associations between SUDs and CODs across such impulsivity subtypes. The abbreviated Barratt impulsiveness scale was used to assess motor and cognitive (attentional and nonplanning) impulsivity, a structured interview for diagnosis of SUD and CODs, and other clinimetric measures for severity of substance use. Latent class analysis was conducted to extract subgroups of impulsivity subtypes and Poisson regression to analyze effects of interactions of classes by CODs on severity of substance use. 568 participants were evaluated. Results featured a four-class model as the best-fitted solution: overall high impulsivity (OHI); overall low impulsivity; high cognitive-low motor impulsivity; and moderate cognitive-low motor impulsivity (MC-LMI). OHI and MC-LMI concentrated on most of the individuals with CODs, and individuals within OHI and MC-LMI showed more severity of substance use. The expression of this severity relative to the impulsivity subtypes was modified by their interaction with internalizing and externalizing CODs in very heterogeneous ways. Our findings suggest that knowing either the presence of trait-based subtypes or CODs in individuals with SUDs is not enough to characterize clinical outcomes, and that the analysis of interactions between psychiatric categories and behavioral traits is necessary to better understand the expressions of psychiatric disorders.
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spelling pubmed-58115142018-02-23 Latent Impulsivity Subtypes in Substance Use Disorders and Interactions with Internalizing and Externalizing Co-Occurring Disorders Marín-Navarrete, Rodrigo Toledo-Fernández, Aldebarán Villalobos-Gallegos, Luis Roncero, Carlos Szerman, Nestor Medina-Mora, María Elena Front Psychiatry Psychiatry This study explored the clinical importance of latent impulsivity subtypes within a sample of individuals with substance use disorders (SUDs) and high rates of co-occurring disorders (CODs) receiving residential treatment, aiming to assess the heterogeneity of the associations between SUDs and CODs across such impulsivity subtypes. The abbreviated Barratt impulsiveness scale was used to assess motor and cognitive (attentional and nonplanning) impulsivity, a structured interview for diagnosis of SUD and CODs, and other clinimetric measures for severity of substance use. Latent class analysis was conducted to extract subgroups of impulsivity subtypes and Poisson regression to analyze effects of interactions of classes by CODs on severity of substance use. 568 participants were evaluated. Results featured a four-class model as the best-fitted solution: overall high impulsivity (OHI); overall low impulsivity; high cognitive-low motor impulsivity; and moderate cognitive-low motor impulsivity (MC-LMI). OHI and MC-LMI concentrated on most of the individuals with CODs, and individuals within OHI and MC-LMI showed more severity of substance use. The expression of this severity relative to the impulsivity subtypes was modified by their interaction with internalizing and externalizing CODs in very heterogeneous ways. Our findings suggest that knowing either the presence of trait-based subtypes or CODs in individuals with SUDs is not enough to characterize clinical outcomes, and that the analysis of interactions between psychiatric categories and behavioral traits is necessary to better understand the expressions of psychiatric disorders. Frontiers Media S.A. 2018-02-09 /pmc/articles/PMC5811514/ /pubmed/29479323 http://dx.doi.org/10.3389/fpsyt.2018.00027 Text en Copyright © 2018 Marín-Navarrete, Toledo-Fernández, Villalobos-Gallegos, Roncero, Szerman and Medina-Mora. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychiatry
Marín-Navarrete, Rodrigo
Toledo-Fernández, Aldebarán
Villalobos-Gallegos, Luis
Roncero, Carlos
Szerman, Nestor
Medina-Mora, María Elena
Latent Impulsivity Subtypes in Substance Use Disorders and Interactions with Internalizing and Externalizing Co-Occurring Disorders
title Latent Impulsivity Subtypes in Substance Use Disorders and Interactions with Internalizing and Externalizing Co-Occurring Disorders
title_full Latent Impulsivity Subtypes in Substance Use Disorders and Interactions with Internalizing and Externalizing Co-Occurring Disorders
title_fullStr Latent Impulsivity Subtypes in Substance Use Disorders and Interactions with Internalizing and Externalizing Co-Occurring Disorders
title_full_unstemmed Latent Impulsivity Subtypes in Substance Use Disorders and Interactions with Internalizing and Externalizing Co-Occurring Disorders
title_short Latent Impulsivity Subtypes in Substance Use Disorders and Interactions with Internalizing and Externalizing Co-Occurring Disorders
title_sort latent impulsivity subtypes in substance use disorders and interactions with internalizing and externalizing co-occurring disorders
topic Psychiatry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811514/
https://www.ncbi.nlm.nih.gov/pubmed/29479323
http://dx.doi.org/10.3389/fpsyt.2018.00027
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