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Candidate-gene based GWAS identifies reproducible DNA markers for metabolic pyrethroid resistance from standing genetic variation in East African Anopheles gambiae
Metabolic resistance to pyrethroid insecticides is widespread in Anopheles mosquitoes and is a major threat to malaria control. DNA markers would aid predictive monitoring of resistance, but few mutations have been discovered outside of insecticide-targeted genes. Isofemale family pools from a wild...
Autores principales: | Weetman, David, Wilding, Craig S., Neafsey, Daniel E., Müller, Pie, Ochomo, Eric, Isaacs, Alison T., Steen, Keith, Rippon, Emily J., Morgan, John C., Mawejje, Henry D., Rigden, Daniel J., Okedi, Loyce M., Donnelly, Martin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811533/ https://www.ncbi.nlm.nih.gov/pubmed/29440767 http://dx.doi.org/10.1038/s41598-018-21265-5 |
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