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Candidate-gene based GWAS identifies reproducible DNA markers for metabolic pyrethroid resistance from standing genetic variation in East African Anopheles gambiae

Metabolic resistance to pyrethroid insecticides is widespread in Anopheles mosquitoes and is a major threat to malaria control. DNA markers would aid predictive monitoring of resistance, but few mutations have been discovered outside of insecticide-targeted genes. Isofemale family pools from a wild...

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Detalles Bibliográficos
Autores principales: Weetman, David, Wilding, Craig S., Neafsey, Daniel E., Müller, Pie, Ochomo, Eric, Isaacs, Alison T., Steen, Keith, Rippon, Emily J., Morgan, John C., Mawejje, Henry D., Rigden, Daniel J., Okedi, Loyce M., Donnelly, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811533/
https://www.ncbi.nlm.nih.gov/pubmed/29440767
http://dx.doi.org/10.1038/s41598-018-21265-5

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