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A sarcopenia screening test predicts mortality in hospitalized older adults

The aim of this study is to investigate the validation of a sarcopenia screening test (Ishii’s formula) for predicting long-term mortality among older adult inpatients. A prospective, observational study was conducted in acute geriatric wards at three hospitals in western China. Sarcopenia was estim...

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Autores principales: Tang, Tianjiao, Wu, Linna, Yang, Ling, Jiang, Jiaojiao, Hao, Qiukui, Dong, Birong, Yang, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811535/
https://www.ncbi.nlm.nih.gov/pubmed/29440681
http://dx.doi.org/10.1038/s41598-018-21237-9
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author Tang, Tianjiao
Wu, Linna
Yang, Ling
Jiang, Jiaojiao
Hao, Qiukui
Dong, Birong
Yang, Ming
author_facet Tang, Tianjiao
Wu, Linna
Yang, Ling
Jiang, Jiaojiao
Hao, Qiukui
Dong, Birong
Yang, Ming
author_sort Tang, Tianjiao
collection PubMed
description The aim of this study is to investigate the validation of a sarcopenia screening test (Ishii’s formula) for predicting long-term mortality among older adult inpatients. A prospective, observational study was conducted in acute geriatric wards at three hospitals in western China. Sarcopenia was estimated using Ishii’s formula. Survival status was assessed at 12, 24, and 36 months after the baseline investigation. Cox proportional-hazard models were applied to calculate the hazard ratio for mortality associated with sarcopenia. Three hundred and eighty participants (100 women) with a mean age of 80.2 ± 7.1 years were included. According to Ishii’s formula, 264 participants (69.5%) were sarcopenic. The prevalence of sarcopenia was similar in men and women (71.1% vs. 65.0%, respectively, P = 0.258). Sixty-seven participants (17.6%) died during the 3-year follow-up period. The all-cause mortality was significantly higher in the sarcopenia group than in the non-sarcopenia group (20.1% vs. 12.1%, respectively, P < 0.05). Multivariate Cox proportional hazards analysis identified sarcopenia as a significant predictor of 3-year all-cause mortality (adjusted hazard ratio [HR]: 2.06; 95% confidence interval [CI]: 1.02–4.15). In conclusion, sarcopenia, estimated by Ishii’s formula, can predict 3-year all-cause mortality in a study population of hospitalized older adults.
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spelling pubmed-58115352018-02-16 A sarcopenia screening test predicts mortality in hospitalized older adults Tang, Tianjiao Wu, Linna Yang, Ling Jiang, Jiaojiao Hao, Qiukui Dong, Birong Yang, Ming Sci Rep Article The aim of this study is to investigate the validation of a sarcopenia screening test (Ishii’s formula) for predicting long-term mortality among older adult inpatients. A prospective, observational study was conducted in acute geriatric wards at three hospitals in western China. Sarcopenia was estimated using Ishii’s formula. Survival status was assessed at 12, 24, and 36 months after the baseline investigation. Cox proportional-hazard models were applied to calculate the hazard ratio for mortality associated with sarcopenia. Three hundred and eighty participants (100 women) with a mean age of 80.2 ± 7.1 years were included. According to Ishii’s formula, 264 participants (69.5%) were sarcopenic. The prevalence of sarcopenia was similar in men and women (71.1% vs. 65.0%, respectively, P = 0.258). Sixty-seven participants (17.6%) died during the 3-year follow-up period. The all-cause mortality was significantly higher in the sarcopenia group than in the non-sarcopenia group (20.1% vs. 12.1%, respectively, P < 0.05). Multivariate Cox proportional hazards analysis identified sarcopenia as a significant predictor of 3-year all-cause mortality (adjusted hazard ratio [HR]: 2.06; 95% confidence interval [CI]: 1.02–4.15). In conclusion, sarcopenia, estimated by Ishii’s formula, can predict 3-year all-cause mortality in a study population of hospitalized older adults. Nature Publishing Group UK 2018-02-13 /pmc/articles/PMC5811535/ /pubmed/29440681 http://dx.doi.org/10.1038/s41598-018-21237-9 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Tang, Tianjiao
Wu, Linna
Yang, Ling
Jiang, Jiaojiao
Hao, Qiukui
Dong, Birong
Yang, Ming
A sarcopenia screening test predicts mortality in hospitalized older adults
title A sarcopenia screening test predicts mortality in hospitalized older adults
title_full A sarcopenia screening test predicts mortality in hospitalized older adults
title_fullStr A sarcopenia screening test predicts mortality in hospitalized older adults
title_full_unstemmed A sarcopenia screening test predicts mortality in hospitalized older adults
title_short A sarcopenia screening test predicts mortality in hospitalized older adults
title_sort sarcopenia screening test predicts mortality in hospitalized older adults
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811535/
https://www.ncbi.nlm.nih.gov/pubmed/29440681
http://dx.doi.org/10.1038/s41598-018-21237-9
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