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Previous Sternotomy as a Risk Factor in Minimally Invasive Mitral Valve Surgery

BACKGROUND: Cardiac redo surgery, especially after a full sternotomy, is considered a high-risk procedure. Minimally invasive mitral valve surgery (MIMVS) is a potential therapeutic approach. However, current developments in interventional cardiology necessitate additional discussion regarding the t...

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Autores principales: Minol, Jan-Philipp, Akhyari, Payam, Boeken, Udo, Albert, Alexander, Rellecke, Philipp, Dimitrova, Vanessa, Sixt, Stephan Urs, Kamiya, Hiroyuki, Lichtenberg, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811546/
https://www.ncbi.nlm.nih.gov/pubmed/29479532
http://dx.doi.org/10.3389/fsurg.2018.00005
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author Minol, Jan-Philipp
Akhyari, Payam
Boeken, Udo
Albert, Alexander
Rellecke, Philipp
Dimitrova, Vanessa
Sixt, Stephan Urs
Kamiya, Hiroyuki
Lichtenberg, Artur
author_facet Minol, Jan-Philipp
Akhyari, Payam
Boeken, Udo
Albert, Alexander
Rellecke, Philipp
Dimitrova, Vanessa
Sixt, Stephan Urs
Kamiya, Hiroyuki
Lichtenberg, Artur
author_sort Minol, Jan-Philipp
collection PubMed
description BACKGROUND: Cardiac redo surgery, especially after a full sternotomy, is considered a high-risk procedure. Minimally invasive mitral valve surgery (MIMVS) is a potential therapeutic approach. However, current developments in interventional cardiology necessitate additional discussion regarding the therapy of choice in high-risk patients. In this context, it is necessary to clarify the perioperative and postoperative risks induced by the factor previous sternotomy in the setting of MIMVS. Thus, we present a comparative study analyzing the outcome of MIMVS after previous sternotomy vs. primary operation. METHODS: We identified 19 patients who received isolated or combined mitral valve (MV) surgery via the MIMVS approach after previous full sternotomy (PS group) and compared the results to those of a group of 357 patients who received primary MIMVS (non-PS group). After a propensity score analysis, groups of n = 15 and n = 131, respectively, were subjected to a comparative evaluation. A 1-year follow-up analysis of functional cardiac parameters and clinical symptoms was performed, accompanied by a Kaplan–Meier analysis. RESULTS: Except for the rate of realized MV reconstructions (PS group: 53.8% vs. non-PS group: 85.5%; p = 0.011), no significant differences were to be noted within the intraoperative and early postoperative course. However, patients in the PS group experienced an increased intensive care unit stay length (PS group: 2 days, 95% CI, 1–8 vs. non-PS group: 1 day, 95% CI, 1–2; p = 0.072). The follow-up examinations revealed excellent functional and clinical outcomes for both groups. The Kaplan–Meier analysis displayed no significant difference regarding the postoperative mortality (p = 0.929) related to the patients at risk. CONCLUSION: A previous sternotomy remains a risk factor for MIMVS and demands special attention in the early postoperative period. Nevertheless, the early- and late-term results concerning the functional and clinical outcomes suggest that the MIMVS procedure is satisfactory, even after a full sternotomy.
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spelling pubmed-58115462018-02-23 Previous Sternotomy as a Risk Factor in Minimally Invasive Mitral Valve Surgery Minol, Jan-Philipp Akhyari, Payam Boeken, Udo Albert, Alexander Rellecke, Philipp Dimitrova, Vanessa Sixt, Stephan Urs Kamiya, Hiroyuki Lichtenberg, Artur Front Surg Surgery BACKGROUND: Cardiac redo surgery, especially after a full sternotomy, is considered a high-risk procedure. Minimally invasive mitral valve surgery (MIMVS) is a potential therapeutic approach. However, current developments in interventional cardiology necessitate additional discussion regarding the therapy of choice in high-risk patients. In this context, it is necessary to clarify the perioperative and postoperative risks induced by the factor previous sternotomy in the setting of MIMVS. Thus, we present a comparative study analyzing the outcome of MIMVS after previous sternotomy vs. primary operation. METHODS: We identified 19 patients who received isolated or combined mitral valve (MV) surgery via the MIMVS approach after previous full sternotomy (PS group) and compared the results to those of a group of 357 patients who received primary MIMVS (non-PS group). After a propensity score analysis, groups of n = 15 and n = 131, respectively, were subjected to a comparative evaluation. A 1-year follow-up analysis of functional cardiac parameters and clinical symptoms was performed, accompanied by a Kaplan–Meier analysis. RESULTS: Except for the rate of realized MV reconstructions (PS group: 53.8% vs. non-PS group: 85.5%; p = 0.011), no significant differences were to be noted within the intraoperative and early postoperative course. However, patients in the PS group experienced an increased intensive care unit stay length (PS group: 2 days, 95% CI, 1–8 vs. non-PS group: 1 day, 95% CI, 1–2; p = 0.072). The follow-up examinations revealed excellent functional and clinical outcomes for both groups. The Kaplan–Meier analysis displayed no significant difference regarding the postoperative mortality (p = 0.929) related to the patients at risk. CONCLUSION: A previous sternotomy remains a risk factor for MIMVS and demands special attention in the early postoperative period. Nevertheless, the early- and late-term results concerning the functional and clinical outcomes suggest that the MIMVS procedure is satisfactory, even after a full sternotomy. Frontiers Media S.A. 2018-02-09 /pmc/articles/PMC5811546/ /pubmed/29479532 http://dx.doi.org/10.3389/fsurg.2018.00005 Text en Copyright © 2018 Minol, Akhyari, Boeken, Albert, Rellecke, Dimitrova, Sixt, Kamiya and Lichtenberg. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Minol, Jan-Philipp
Akhyari, Payam
Boeken, Udo
Albert, Alexander
Rellecke, Philipp
Dimitrova, Vanessa
Sixt, Stephan Urs
Kamiya, Hiroyuki
Lichtenberg, Artur
Previous Sternotomy as a Risk Factor in Minimally Invasive Mitral Valve Surgery
title Previous Sternotomy as a Risk Factor in Minimally Invasive Mitral Valve Surgery
title_full Previous Sternotomy as a Risk Factor in Minimally Invasive Mitral Valve Surgery
title_fullStr Previous Sternotomy as a Risk Factor in Minimally Invasive Mitral Valve Surgery
title_full_unstemmed Previous Sternotomy as a Risk Factor in Minimally Invasive Mitral Valve Surgery
title_short Previous Sternotomy as a Risk Factor in Minimally Invasive Mitral Valve Surgery
title_sort previous sternotomy as a risk factor in minimally invasive mitral valve surgery
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811546/
https://www.ncbi.nlm.nih.gov/pubmed/29479532
http://dx.doi.org/10.3389/fsurg.2018.00005
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