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Rpb9-deficient cells are defective in DNA damage response and require histone H3 acetylation for survival

Rpb9 is a non-essential subunit of RNA polymerase II that is involved in DNA transcription and repair. In budding yeast, deletion of RPB9 causes several phenotypes such as slow growth and temperature sensitivity. We found that simultaneous mutation of multiple N-terminal lysines within histone H3 wa...

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Detalles Bibliográficos
Autores principales: Sein, Henel, Reinmets, Kristina, Peil, Kadri, Kristjuhan, Kersti, Värv, Signe, Kristjuhan, Arnold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811553/
https://www.ncbi.nlm.nih.gov/pubmed/29440683
http://dx.doi.org/10.1038/s41598-018-21110-9