Ectopic expression of S28A-mutated Histone H3 modulates longevity, stress resistance and cardiac function in Drosophila

Histone H3 serine 28 (H3S28) phosphorylation and de-repression of polycomb repressive complex (PRC)-mediated gene regulation is linked to stress conditions in mitotic and post-mitotic cells. To better understand the role of H3S28 phosphorylation in vivo, we studied a Drosophila strain with ectopic e...

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Detalles Bibliográficos
Autores principales: Joos, J. P., Saadatmand, A. R., Schnabel, C., Viktorinová, I., Brand, T., Kramer, M., Nattel, S., Dobrev, D., Tomancak, P., Backs, J., Kleinbongard, P., Heusch, G., Lorenz, K., Koch, E., Weber, S., El-Armouche, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811592/
https://www.ncbi.nlm.nih.gov/pubmed/29440697
http://dx.doi.org/10.1038/s41598-018-21372-3

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