Cargando…
Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids
Here we describe a method for fabricating a primary human Small Intestine-on-a-Chip (Intestine Chip) containing epithelial cells isolated from healthy regions of intestinal biopsies. The primary epithelial cells are expanded as 3D organoids, dissociated, and cultured on a porous membrane within a mi...
Autores principales: | Kasendra, Magdalena, Tovaglieri, Alessio, Sontheimer-Phelps, Alexandra, Jalili-Firoozinezhad, Sasan, Bein, Amir, Chalkiadaki, Angeliki, Scholl, William, Zhang, Cheng, Rickner, Hannah, Richmond, Camilla A., Li, Hu, Breault, David T., Ingber, Donald E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811607/ https://www.ncbi.nlm.nih.gov/pubmed/29440725 http://dx.doi.org/10.1038/s41598-018-21201-7 |
Ejemplares similares
-
Microfluidic Organ-on-a-Chip Models of Human Intestine
por: Bein, Amir, et al.
Publicado: (2018) -
Human Colon-on-a-Chip Enables Continuous In Vitro Analysis of Colon Mucus Layer Accumulation and Physiology
por: Sontheimer-Phelps, Alexandra, et al.
Publicado: (2019) -
Species-specific enhancement of enterohemorrhagic E. coli pathogenesis mediated by microbiome metabolites
por: Tovaglieri, Alessio, et al.
Publicado: (2019) -
A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip
por: Jalili-Firoozinezhad, Sasan, et al.
Publicado: (2019) -
Move Over Caco-2 Cells: Human-Induced Organoids Meet Gut-on-a-Chip
por: Richmond, Camilla A., et al.
Publicado: (2018)