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Genomewide Transcriptional Responses of Iron-Starved Chlamydia trachomatis Reveal Prioritization of Metabolic Precursor Synthesis over Protein Translation

Iron is essential for growth and development of Chlamydia. Its long-term starvation in cultured mammalian cells leads to production of aberrant noninfectious chlamydial forms, also known as persistence. Immediate transcriptional responses to iron limitation have not been characterized, leaving a kno...

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Detalles Bibliográficos
Autores principales: Brinkworth, Amanda J., Wildung, Mark R., Carabeo, Rey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811630/
https://www.ncbi.nlm.nih.gov/pubmed/29468197
http://dx.doi.org/10.1128/mSystems.00184-17