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The role of NAFLD in cardiometabolic disease: an update
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the world, yet the complex pathogenesis remains to be fully elucidated. The prevalence of NAFLD has risen precipitously in recent years and is now a leading indication for liver transplantation. New waitli...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811670/ https://www.ncbi.nlm.nih.gov/pubmed/29497497 http://dx.doi.org/10.12688/f1000research.12028.1 |
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author | Faasse, Sarah Braun, Hayley Vos, Miriam |
author_facet | Faasse, Sarah Braun, Hayley Vos, Miriam |
author_sort | Faasse, Sarah |
collection | PubMed |
description | Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the world, yet the complex pathogenesis remains to be fully elucidated. The prevalence of NAFLD has risen precipitously in recent years and is now a leading indication for liver transplantation. New waitlist registrants with non-alcoholic steatohepatitis–induced cirrhosis increased by 170% from 2004 to 2013. In addition, patients with NAFLD are at increased risk of both cardiovascular disease and type II diabetes. In this update, recent studies contributing to the understanding of the place of NAFLD in cardiometabolic disease will be discussed. |
format | Online Article Text |
id | pubmed-5811670 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | F1000 Research Limited |
record_format | MEDLINE/PubMed |
spelling | pubmed-58116702018-02-28 The role of NAFLD in cardiometabolic disease: an update Faasse, Sarah Braun, Hayley Vos, Miriam F1000Res Review Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the world, yet the complex pathogenesis remains to be fully elucidated. The prevalence of NAFLD has risen precipitously in recent years and is now a leading indication for liver transplantation. New waitlist registrants with non-alcoholic steatohepatitis–induced cirrhosis increased by 170% from 2004 to 2013. In addition, patients with NAFLD are at increased risk of both cardiovascular disease and type II diabetes. In this update, recent studies contributing to the understanding of the place of NAFLD in cardiometabolic disease will be discussed. F1000 Research Limited 2018-02-09 /pmc/articles/PMC5811670/ /pubmed/29497497 http://dx.doi.org/10.12688/f1000research.12028.1 Text en Copyright: © 2018 Faasse S et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Faasse, Sarah Braun, Hayley Vos, Miriam The role of NAFLD in cardiometabolic disease: an update |
title | The role of NAFLD in cardiometabolic disease: an update |
title_full | The role of NAFLD in cardiometabolic disease: an update |
title_fullStr | The role of NAFLD in cardiometabolic disease: an update |
title_full_unstemmed | The role of NAFLD in cardiometabolic disease: an update |
title_short | The role of NAFLD in cardiometabolic disease: an update |
title_sort | role of nafld in cardiometabolic disease: an update |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811670/ https://www.ncbi.nlm.nih.gov/pubmed/29497497 http://dx.doi.org/10.12688/f1000research.12028.1 |
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