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CellMap visualizes protein-protein interactions and subcellular localization

Many tools visualize protein-protein interaction (PPI) networks. The tool introduced here, CellMap, adds one crucial novelty by visualizing PPI networks in the context of subcellular localization, i.e. the location in the cell or cellular component in which a PPI happens. Users can upload images of...

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Detalles Bibliográficos
Autores principales: Dallago, Christian, Goldberg, Tatyana, Andrade-Navarro, Miguel Angel, Alanis-Lobato, Gregorio, Rost, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811672/
https://www.ncbi.nlm.nih.gov/pubmed/29497493
http://dx.doi.org/10.12688/f1000research.12707.2
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author Dallago, Christian
Goldberg, Tatyana
Andrade-Navarro, Miguel Angel
Alanis-Lobato, Gregorio
Rost, Burkhard
author_facet Dallago, Christian
Goldberg, Tatyana
Andrade-Navarro, Miguel Angel
Alanis-Lobato, Gregorio
Rost, Burkhard
author_sort Dallago, Christian
collection PubMed
description Many tools visualize protein-protein interaction (PPI) networks. The tool introduced here, CellMap, adds one crucial novelty by visualizing PPI networks in the context of subcellular localization, i.e. the location in the cell or cellular component in which a PPI happens. Users can upload images of cells and define areas of interest against which PPIs for selected proteins are displayed (by default on a cartoon of a cell). Annotations of localization are provided by the user or through our in-house database. The visualizer and server are written in JavaScript, making CellMap easy to customize and to extend by researchers and developers.
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spelling pubmed-58116722018-02-28 CellMap visualizes protein-protein interactions and subcellular localization Dallago, Christian Goldberg, Tatyana Andrade-Navarro, Miguel Angel Alanis-Lobato, Gregorio Rost, Burkhard F1000Res Software Tool Article Many tools visualize protein-protein interaction (PPI) networks. The tool introduced here, CellMap, adds one crucial novelty by visualizing PPI networks in the context of subcellular localization, i.e. the location in the cell or cellular component in which a PPI happens. Users can upload images of cells and define areas of interest against which PPIs for selected proteins are displayed (by default on a cartoon of a cell). Annotations of localization are provided by the user or through our in-house database. The visualizer and server are written in JavaScript, making CellMap easy to customize and to extend by researchers and developers. F1000 Research Limited 2018-02-01 /pmc/articles/PMC5811672/ /pubmed/29497493 http://dx.doi.org/10.12688/f1000research.12707.2 Text en Copyright: © 2018 Dallago C et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Software Tool Article
Dallago, Christian
Goldberg, Tatyana
Andrade-Navarro, Miguel Angel
Alanis-Lobato, Gregorio
Rost, Burkhard
CellMap visualizes protein-protein interactions and subcellular localization
title CellMap visualizes protein-protein interactions and subcellular localization
title_full CellMap visualizes protein-protein interactions and subcellular localization
title_fullStr CellMap visualizes protein-protein interactions and subcellular localization
title_full_unstemmed CellMap visualizes protein-protein interactions and subcellular localization
title_short CellMap visualizes protein-protein interactions and subcellular localization
title_sort cellmap visualizes protein-protein interactions and subcellular localization
topic Software Tool Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811672/
https://www.ncbi.nlm.nih.gov/pubmed/29497493
http://dx.doi.org/10.12688/f1000research.12707.2
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