Polygenic risk scores for schizophrenia and bipolar disorder associate with addiction

We use polygenic risk scores (PRSs) for schizophrenia (SCZ) and bipolar disorder (BPD) to predict smoking, and addiction to nicotine, alcohol or drugs in individuals not diagnosed with psychotic disorders. Using PRSs for 144 609 subjects, including 10 036 individuals admitted for in‐patient addictio...

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Detalles Bibliográficos
Autores principales: Reginsson, Gunnar W., Ingason, Andres, Euesden, Jack, Bjornsdottir, Gyda, Olafsson, Sigurgeir, Sigurdsson, Engilbert, Oskarsson, Hogni, Tyrfingsson, Thorarinn, Runarsdottir, Valgerdur, Hansdottir, Ingunn, Steinberg, Stacy, Stefansson, Hreinn, Gudbjartsson, Daniel F., Thorgeirsson, Thorgeir E., Stefansson, Kari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Genetic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811785/
https://www.ncbi.nlm.nih.gov/pubmed/28231610
http://dx.doi.org/10.1111/adb.12496

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