Cargando…
Impact of PKCε downregulation on autophagy in glioblastoma cells
BACKGROUND: Several efforts have been focused on identification of pathways involved in malignancy, progression, and response to treatment in Glioblastoma (GB). Overexpression of PKCε was detected in histological samples from GB, anaplastic astrocytoma, and gliosarcoma and is considered an important...
Autores principales: | Toton, Ewa, Romaniuk, Aleksandra, Konieczna, Natalia, Hofmann, Johann, Barciszewski, Jan, Rybczynska, Maria |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811983/ https://www.ncbi.nlm.nih.gov/pubmed/29439667 http://dx.doi.org/10.1186/s12885-018-4095-1 |
Ejemplares similares
-
hTERT Downregulation Attenuates Resistance to DOX, Impairs FAK-Mediated Adhesion, and Leads to Autophagy Induction in Breast Cancer Cells
por: Romaniuk-Drapała, Aleksandra, et al.
Publicado: (2021) -
Telomerase downregulation induces proapoptotic genes expression and initializes breast cancer cells apoptosis followed by DNA fragmentation in a cell type dependent manner
por: Rubis, Blazej, et al.
Publicado: (2013) -
The tetramethoxyflavone zapotin selectively activates protein kinase C epsilon, leading to its down-modulation accompanied by Bcl-2, c-Jun and c-Fos decrease
por: Toton, Ewa, et al.
Publicado: (2012) -
Telomerase Inhibitor TMPyP4 Alters Adhesion and Migration of Breast-Cancer Cells MCF7 and MDA-MB-231
por: Konieczna, Natalia, et al.
Publicado: (2019) -
Thienoquinolines as Novel
Disruptors of the PKCε/RACK2 Protein–Protein Interaction
por: Rechfeld, Florian, et al.
Publicado: (2014)