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A 42-year-old woman with subacute reversible dementia: A cautionary tale

A 42-year-old woman presented with a 6-month history of diffuse headache of moderate intensity and gradual onset of generalized weakness, imbalance, apathy, memory decline, hypophonia, dysphagia, constipation and urinary incontinence. Clinical examination revealed several elements of a frontal lobe...

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Autores principales: Kamtchum-Tatuene, Joseph, Kamwezi, Richard, Nyalubwe, Thokozani, Banda, Josephine P, Mwangalika, Gloria, Matandika, Ian, Hemmila, Ulla, Tisell, Magnus, Koponen, Susanna, Benjamin, Laura A, Kamalo, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Medical Association Of Malawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812000/
https://www.ncbi.nlm.nih.gov/pubmed/29872518
http://dx.doi.org/10.4314/mmj.v29i3.7
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author Kamtchum-Tatuene, Joseph
Kamwezi, Richard
Nyalubwe, Thokozani
Banda, Josephine P
Mwangalika, Gloria
Matandika, Ian
Hemmila, Ulla
Tisell, Magnus
Koponen, Susanna
Benjamin, Laura A
Kamalo, Patrick
author_facet Kamtchum-Tatuene, Joseph
Kamwezi, Richard
Nyalubwe, Thokozani
Banda, Josephine P
Mwangalika, Gloria
Matandika, Ian
Hemmila, Ulla
Tisell, Magnus
Koponen, Susanna
Benjamin, Laura A
Kamalo, Patrick
author_sort Kamtchum-Tatuene, Joseph
collection PubMed
description A 42-year-old woman presented with a 6-month history of diffuse headache of moderate intensity and gradual onset of generalized weakness, imbalance, apathy, memory decline, hypophonia, dysphagia, constipation and urinary incontinence. Clinical examination revealed several elements of a frontal lobe dysfunction including apathy with motor impersistence, presence of primitive reflexes, generalized hyperreflexia with bilateral Hoffman sign and ankle clonus. The biological workup was unremarkable and a brain computed tomography scan identified a giant olfactory groove meningioma. A prompt neurosurgical intervention helped to reverse the symptoms. This case illustrates the benefits of actively looking for treatable conditions in young patients presenting with acute or subacute dementia and emphasizes the pivotal role of early brain imaging.
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spelling pubmed-58120002018-06-05 A 42-year-old woman with subacute reversible dementia: A cautionary tale Kamtchum-Tatuene, Joseph Kamwezi, Richard Nyalubwe, Thokozani Banda, Josephine P Mwangalika, Gloria Matandika, Ian Hemmila, Ulla Tisell, Magnus Koponen, Susanna Benjamin, Laura A Kamalo, Patrick Malawi Med J Case Report A 42-year-old woman presented with a 6-month history of diffuse headache of moderate intensity and gradual onset of generalized weakness, imbalance, apathy, memory decline, hypophonia, dysphagia, constipation and urinary incontinence. Clinical examination revealed several elements of a frontal lobe dysfunction including apathy with motor impersistence, presence of primitive reflexes, generalized hyperreflexia with bilateral Hoffman sign and ankle clonus. The biological workup was unremarkable and a brain computed tomography scan identified a giant olfactory groove meningioma. A prompt neurosurgical intervention helped to reverse the symptoms. This case illustrates the benefits of actively looking for treatable conditions in young patients presenting with acute or subacute dementia and emphasizes the pivotal role of early brain imaging. The Medical Association Of Malawi 2017-09 /pmc/articles/PMC5812000/ /pubmed/29872518 http://dx.doi.org/10.4314/mmj.v29i3.7 Text en 2017 The College of Medicine and the Medical Association of Malawi © 2017 The College of Medicine and the Medical Association of Malawi. This work is licensed under the Creative Commons Attribution 4.0 International License. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Case Report
Kamtchum-Tatuene, Joseph
Kamwezi, Richard
Nyalubwe, Thokozani
Banda, Josephine P
Mwangalika, Gloria
Matandika, Ian
Hemmila, Ulla
Tisell, Magnus
Koponen, Susanna
Benjamin, Laura A
Kamalo, Patrick
A 42-year-old woman with subacute reversible dementia: A cautionary tale
title A 42-year-old woman with subacute reversible dementia: A cautionary tale
title_full A 42-year-old woman with subacute reversible dementia: A cautionary tale
title_fullStr A 42-year-old woman with subacute reversible dementia: A cautionary tale
title_full_unstemmed A 42-year-old woman with subacute reversible dementia: A cautionary tale
title_short A 42-year-old woman with subacute reversible dementia: A cautionary tale
title_sort 42-year-old woman with subacute reversible dementia: a cautionary tale
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812000/
https://www.ncbi.nlm.nih.gov/pubmed/29872518
http://dx.doi.org/10.4314/mmj.v29i3.7
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