Synthesis of G0 aminopolyol and aminosugar dendrimers, controlled by NMR and MALDI TOF mass spectrometry

Organic compounds designed to serve as stable dendrimer cores were developed. A series of aminosugar and amino polyol containing G0 dendrimers were synthesized. The reaction mixture composition was checked by MALDI TOF mass spectrometry, while that of purified products – by (1)H and (13)C NMR combin...

Descripción completa

Detalles Bibliográficos
Autores principales: Pyziak, Mikołaj A., Bartkowiak, Grażyna, Popenda, Łukasz, Jurga, Stefan, Schroeder, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812123/
https://www.ncbi.nlm.nih.gov/pubmed/29491788
http://dx.doi.org/10.1080/15685551.2016.1231048
_version_ 1783299983549661184
author Pyziak, Mikołaj A.
Bartkowiak, Grażyna
Popenda, Łukasz
Jurga, Stefan
Schroeder, Grzegorz
author_facet Pyziak, Mikołaj A.
Bartkowiak, Grażyna
Popenda, Łukasz
Jurga, Stefan
Schroeder, Grzegorz
author_sort Pyziak, Mikołaj A.
collection PubMed
description Organic compounds designed to serve as stable dendrimer cores were developed. A series of aminosugar and amino polyol containing G0 dendrimers were synthesized. The reaction mixture composition was checked by MALDI TOF mass spectrometry, while that of purified products – by (1)H and (13)C NMR combined with 2D NMR spectroscopy as well as MALDI TOF MSMS mass spectra. Mass spectrometric fragmentation experiments were performed in positive ion mode in order to determine common fragmentation patterns of [M+H](+) ions.
format Online
Article
Text
id pubmed-5812123
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Taylor & Francis
record_format MEDLINE/PubMed
spelling pubmed-58121232018-02-28 Synthesis of G0 aminopolyol and aminosugar dendrimers, controlled by NMR and MALDI TOF mass spectrometry Pyziak, Mikołaj A. Bartkowiak, Grażyna Popenda, Łukasz Jurga, Stefan Schroeder, Grzegorz Des Monomers Polym Articles Organic compounds designed to serve as stable dendrimer cores were developed. A series of aminosugar and amino polyol containing G0 dendrimers were synthesized. The reaction mixture composition was checked by MALDI TOF mass spectrometry, while that of purified products – by (1)H and (13)C NMR combined with 2D NMR spectroscopy as well as MALDI TOF MSMS mass spectra. Mass spectrometric fragmentation experiments were performed in positive ion mode in order to determine common fragmentation patterns of [M+H](+) ions. Taylor & Francis 2016-10-14 /pmc/articles/PMC5812123/ /pubmed/29491788 http://dx.doi.org/10.1080/15685551.2016.1231048 Text en © 2016 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Pyziak, Mikołaj A.
Bartkowiak, Grażyna
Popenda, Łukasz
Jurga, Stefan
Schroeder, Grzegorz
Synthesis of G0 aminopolyol and aminosugar dendrimers, controlled by NMR and MALDI TOF mass spectrometry
title Synthesis of G0 aminopolyol and aminosugar dendrimers, controlled by NMR and MALDI TOF mass spectrometry
title_full Synthesis of G0 aminopolyol and aminosugar dendrimers, controlled by NMR and MALDI TOF mass spectrometry
title_fullStr Synthesis of G0 aminopolyol and aminosugar dendrimers, controlled by NMR and MALDI TOF mass spectrometry
title_full_unstemmed Synthesis of G0 aminopolyol and aminosugar dendrimers, controlled by NMR and MALDI TOF mass spectrometry
title_short Synthesis of G0 aminopolyol and aminosugar dendrimers, controlled by NMR and MALDI TOF mass spectrometry
title_sort synthesis of g0 aminopolyol and aminosugar dendrimers, controlled by nmr and maldi tof mass spectrometry
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812123/
https://www.ncbi.nlm.nih.gov/pubmed/29491788
http://dx.doi.org/10.1080/15685551.2016.1231048
work_keys_str_mv AT pyziakmikołaja synthesisofg0aminopolyolandaminosugardendrimerscontrolledbynmrandmalditofmassspectrometry
AT bartkowiakgrazyna synthesisofg0aminopolyolandaminosugardendrimerscontrolledbynmrandmalditofmassspectrometry
AT popendałukasz synthesisofg0aminopolyolandaminosugardendrimerscontrolledbynmrandmalditofmassspectrometry
AT jurgastefan synthesisofg0aminopolyolandaminosugardendrimerscontrolledbynmrandmalditofmassspectrometry
AT schroedergrzegorz synthesisofg0aminopolyolandaminosugardendrimerscontrolledbynmrandmalditofmassspectrometry

Ejemplares similares