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High Fat Diet Attenuates the Anticontractile Activity of Aortic PVAT via a Mechanism Involving AMPK and Reduced Adiponectin Secretion
Background and aim: Perivascular adipose tissue (PVAT) positively regulates vascular function through production of factors such as adiponectin but this effect is attenuated in obesity. The enzyme AMP-activated protein kinase (AMPK) is present in PVAT and is implicated in mediating the vascular effe...
Autores principales: | Almabrouk, Tarek A. M., White, Anna D., Ugusman, Azizah B., Skiba, Dominik S., Katwan, Omar J., Alganga, Husam, Guzik, Tomasz J., Touyz, Rhian M., Salt, Ian P., Kennedy, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812172/ https://www.ncbi.nlm.nih.gov/pubmed/29479319 http://dx.doi.org/10.3389/fphys.2018.00051 |
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