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Expression profiling of chromatin-modifying enzymes and global DNA methylation in CD4+ T cells from patients with chronic HIV infection at different HIV control and progression states
BACKGROUND: Integration of human immunodeficiency virus type 1 (HIV-1) into the host genome causes global disruption of the chromatin environment. The abundance level of various chromatin-modifying enzymes produces these alterations and affects both the provirus and cellular gene expression. Here, w...
Autores principales: | Bogoi, Roberta Nicoleta, de Pablo, Alicia, Valencia, Eulalia, Martín-Carbonero, Luz, Moreno, Victoria, Vilchez-Rueda, Helem Haydee, Asensi, Victor, Rodriguez, Rosa, Toledano, Victor, Rodés, Berta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812196/ https://www.ncbi.nlm.nih.gov/pubmed/29449904 http://dx.doi.org/10.1186/s13148-018-0448-5 |
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