Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows

No immunogen to date has reliably elicited broadly neutralizing antibodies (bnAbs) to HIV in humans or animal models. Advances in the design of immunogens (BG505 SOSIP) that antigenically mimic the HIV envelope glycoprotein (Env)(1) have improved the elicitation of potent isolate-specific Ab respons...

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Detalles Bibliográficos
Autores principales: Sok, Devin, Le, Khoa M., Vadnais, Melissa, Saye-Francisco, Karen, Jardine, Joseph G., Torres, Jonathan, Berndsen, Zachary T., Kong, Leopold, Stanfield, Robyn, Ruiz, Jennifer, Ramos, Alejandra, Liang, Chi-Hui, Chen, Patricia L., Criscitiello, Michael F., Mwangi, Waithaka, Wilson, Ian A., Ward, Andrew B., Smider, Vaughn V., Burton, Dennis R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812458/
https://www.ncbi.nlm.nih.gov/pubmed/28726771
http://dx.doi.org/10.1038/nature23301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812458/
https://www.ncbi.nlm.nih.gov/pubmed/28726771
http://dx.doi.org/10.1038/nature23301

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