CRISPR/Cas system for yeast genome engineering: advances and applications

The methods based on the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) system have quickly gained popularity for genome editing and transcriptional regulation in many organisms, including yeast. This review aims to provide a comprehensive overview of CRIS...

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Detalles Bibliográficos
Autores principales: Stovicek, Vratislav, Holkenbrink, Carina, Borodina, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812514/
https://www.ncbi.nlm.nih.gov/pubmed/28505256
http://dx.doi.org/10.1093/femsyr/fox030
Descripción
Sumario:The methods based on the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) system have quickly gained popularity for genome editing and transcriptional regulation in many organisms, including yeast. This review aims to provide a comprehensive overview of CRISPR application for different yeast species: from basic principles and genetic design to applications.

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