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Mutagenesis and expression of methane monooxygenase to alter regioselectivity with aromatic substrates

Soluble methane monooxygenase (sMMO) from methane-oxidising bacteria can oxygenate more than 100 hydrocarbons and is one of the most catalytically versatile biological oxidation catalysts. Expression of recombinant sMMO has to date not been achieved in Escherichia coli and so an alternative expressi...

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Detalles Bibliográficos
Autores principales: Lock, Malcolm, Nichol, Tim, Murrell, J. Colin, Smith, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812538/
https://www.ncbi.nlm.nih.gov/pubmed/28854685
http://dx.doi.org/10.1093/femsle/fnx137