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Bone marrow mesenchymal stem cell-derived exosomal miR-21 protects C-kit(+) cardiac stem cells from oxidative injury through the PTEN/PI3K/Akt axis
Stem cell (SC) therapy for ischemic cardiomyopathy is hampered by poor survival of the implanted cells. Recently, SC-derived exosomes have been shown to facilitate cell proliferation and survival by transporting various proteins and non-coding RNAs (such as microRNAs and lncRNAs). In this study, miR...
Autores principales: | Shi, Bei, Wang, Yan, Zhao, Ranzhun, Long, Xianping, Deng, Wenwen, Wang, Zhenglong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812567/ https://www.ncbi.nlm.nih.gov/pubmed/29444190 http://dx.doi.org/10.1371/journal.pone.0191616 |
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