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ShDcR3 sensitizes TRAIL-resistant HCC cells by inducing caspase-dependent apoptosis while suppressing NF-κB dependent cFLIP(L) expression

Evidence has shown that most hepatocellular carcinoma (HCC) cells are resistant to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis. However, the molecular mechanisms underlying TRAIL-mediated apoptosis resistance are not well understood. In this study, we rep...

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Detalles Bibliográficos
Autores principales:	Liang, Dong-Yu, Huang, Wei, Chang, Qing, Hou, Yan-Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812574/ https://www.ncbi.nlm.nih.gov/pubmed/29444104 http://dx.doi.org/10.1371/journal.pone.0191545

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