Reduced cognitive function, increased blood-brain-barrier transport and inflammatory responses, and altered brain metabolites in LDLr -/-and C57BL/6 mice fed a western diet

Recent work suggests that diet affects brain metabolism thereby impacting cognitive function. Our objective was to determine if a western diet altered brain metabolism, increased blood-brain barrier (BBB) transport and inflammation, and induced cognitive impairment in C57BL/6 (WT) mice and low-densi...

Descripción completa

Detalles Bibliográficos
Autores principales: Rutkowsky, Jennifer M., Lee, Linda L., Puchowicz, Michelle, Golub, Mari S., Befroy, Douglas E., Wilson, Dennis W., Anderson, Steven, Cline, Gary, Bini, Jason, Borkowski, Kamil, Knotts, Trina A., Rutledge, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812615/
https://www.ncbi.nlm.nih.gov/pubmed/29444171
http://dx.doi.org/10.1371/journal.pone.0191909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812615/
https://www.ncbi.nlm.nih.gov/pubmed/29444171
http://dx.doi.org/10.1371/journal.pone.0191909

Ejemplares similares