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Reduced cognitive function, increased blood-brain-barrier transport and inflammatory responses, and altered brain metabolites in LDLr -/-and C57BL/6 mice fed a western diet
Recent work suggests that diet affects brain metabolism thereby impacting cognitive function. Our objective was to determine if a western diet altered brain metabolism, increased blood-brain barrier (BBB) transport and inflammation, and induced cognitive impairment in C57BL/6 (WT) mice and low-densi...
Autores principales: | Rutkowsky, Jennifer M., Lee, Linda L., Puchowicz, Michelle, Golub, Mari S., Befroy, Douglas E., Wilson, Dennis W., Anderson, Steven, Cline, Gary, Bini, Jason, Borkowski, Kamil, Knotts, Trina A., Rutledge, John C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812615/ https://www.ncbi.nlm.nih.gov/pubmed/29444171 http://dx.doi.org/10.1371/journal.pone.0191909 |
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