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A Selection Operator for Summary Association Statistics Reveals Allelic Heterogeneity of Complex Traits

In recent years, as a secondary analysis in genome-wide association studies (GWASs), conditional and joint multiple-SNP analysis (GCTA-COJO) has been successful in allowing the discovery of additional association signals within detected loci. This suggests that many loci mapped in GWASs harbor more...

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Detalles Bibliográficos
Autores principales: Ning, Zheng, Lee, Youngjo, Joshi, Peter K., Wilson, James F., Pawitan, Yudi, Shen, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812891/
https://www.ncbi.nlm.nih.gov/pubmed/29198721
http://dx.doi.org/10.1016/j.ajhg.2017.09.027