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VPS35 depletion does not impair presynaptic structure and function

The endosomal system is proposed as a mediator of synaptic vesicle recycling, but the molecular recycling mechanism remains largely unknown. Retromer is a key protein complex which mediates endosomal recycling in eukaryotic cells, including neurons. Retromer is important for brain function and mutat...

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Detalles Bibliográficos
Autores principales: Vazquez-Sanchez, Sonia, Bobeldijk, Sander, Dekker, Marien P., van Keimpema, Linda, van Weering, Jan R. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812998/
https://www.ncbi.nlm.nih.gov/pubmed/29445238
http://dx.doi.org/10.1038/s41598-018-20448-4