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Permeability and ammonia selectivity in aquaporin TIP2;1: linking structure to function

Aquaporin TIP2;1 is a protein channel permeable to both water and ammonia. The structural origin of ammonia selectivity remains obscure, but experiments have revealed that a double mutation renders it impermeable to ammonia without affecting water permeability. Here, we aim to reproduce and explain...

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Detalles Bibliográficos
Autores principales: Lindahl, Viveca, Gourdon, Pontus, Andersson, Magnus, Hess, Berk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813003/
https://www.ncbi.nlm.nih.gov/pubmed/29445244
http://dx.doi.org/10.1038/s41598-018-21357-2