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Permeability and ammonia selectivity in aquaporin TIP2;1: linking structure to function
Aquaporin TIP2;1 is a protein channel permeable to both water and ammonia. The structural origin of ammonia selectivity remains obscure, but experiments have revealed that a double mutation renders it impermeable to ammonia without affecting water permeability. Here, we aim to reproduce and explain...
Autores principales: | Lindahl, Viveca, Gourdon, Pontus, Andersson, Magnus, Hess, Berk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813003/ https://www.ncbi.nlm.nih.gov/pubmed/29445244 http://dx.doi.org/10.1038/s41598-018-21357-2 |
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