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ACKR2 in hematopoietic precursors as a checkpoint of neutrophil release and anti-metastatic activity
Atypical chemokine receptors (ACKRs) are regulators of leukocyte traffic, inflammation, and immunity. ACKR2 is a scavenger for most inflammatory CC chemokines and is a negative regulator of inflammation. Here we report that ACKR2 is expressed in hematopoietic precursors and downregulated during myel...
Autores principales: | Massara, Matteo, Bonavita, Ornella, Savino, Benedetta, Caronni, Nicoletta, Mollica Poeta, Valeria, Sironi, Marina, Setten, Elisa, Recordati, Camilla, Crisafulli, Laura, Ficara, Francesca, Mantovani, Alberto, Locati, Massimo, Bonecchi, Raffaella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813042/ https://www.ncbi.nlm.nih.gov/pubmed/29445158 http://dx.doi.org/10.1038/s41467-018-03080-8 |
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