Single‐dose euglycaemic clamp studies demonstrating pharmacokinetic and pharmacodynamic similarity between MK‐1293 insulin glargine and originator insulin glargine (Lantus) in subjects with type 1 diabetes and healthy subjects

AIMS: MK‐1293 is an insulin glargine that has an amino acid sequence identical to that of Lantus, the originator insulin glargine. Two euglycaemic clamp studies, 1 in subjects with type 1 diabetes (T1D) and 1 in healthy subjects, were conducted to demonstrate pharmacokinetic (PK) and pharmacodynamic...

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Detalles Bibliográficos
Autores principales: Crutchlow, Michael F., Palcza, John S., Mostoller, Kate M., Mahon, Chantal D., Barbour, April M., Marcos, Michael C., Xu, Yang, Watkins, Elaine, Morrow, Linda, Hompesch, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813203/
https://www.ncbi.nlm.nih.gov/pubmed/28817223
http://dx.doi.org/10.1111/dom.13084

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