Cargando…

Estimation of a significance threshold for epigenome‐wide association studies

Epigenome‐wide association studies (EWAS) are designed to characterise population‐level epigenetic differences across the genome and link them to disease. Most commonly, they assess DNA‐methylation status at cytosine‐guanine dinucleotide (CpG) sites, using platforms such as the Illumina 450k array t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Saffari, Ayden, Silver, Matt J., Zavattari, Patrizia, Moi, Loredana, Columbano, Amedeo, Meaburn, Emma L., Dudbridge, Frank
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813244/ https://www.ncbi.nlm.nih.gov/pubmed/29034560 http://dx.doi.org/10.1002/gepi.22086

Ejemplares similares

Estimation of significance thresholds for genomewide association scans
por: Dudbridge, Frank, et al.
Publicado: (2008)

RNA sequencing of identical twins discordant for autism reveals blood-based signatures implicating immune and transcriptional dysregulation
por: Saffari, Ayden, et al.
Publicado: (2019)

DNA methylation alterations at RE1-silencing transcription factor binding sites and their flanking regions in cancer
por: Vega-Benedetti, Ana Florencia, et al.
Publicado: (2023)

Estimation of a significance threshold for genome-wide association studies
por: Kaler, Avjinder S., et al.
Publicado: (2019)

Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures
por: Wang, Xinchen, et al.
Publicado: (2016)

Integrated DNA methylation analysis identifies topographical and tumoral biomarkers in pilocytic astrocytomas
por: Antonelli, Manila, et al.
Publicado: (2018)

Empirical estimation of genome-wide significance thresholds based on the 1000 Genomes Project data set
por: Kanai, Masahiro, et al.
Publicado: (2016)

Methods for Dealing With Missing Covariate Data in Epigenome-Wide Association Studies
por: Mills, Harriet L, et al.
Publicado: (2019)

Estimands in epigenome-wide association studies
por: Kruppa, Jochen, et al.
Publicado: (2021)

HLA-C dysregulation as a possible mechanism of immune evasion in SARS-CoV-2 and other RNA-virus infections
por: Loi, Eleonora, et al.
Publicado: (2022)

Genome‐Wide Association Study of Latent Cognitive Measures in Adolescence: Genetic Overlap With Intelligence and Education
por: Donati, Georgina, et al.
Publicado: (2019)

Epigenomics of Pancreatic Cancer: A Critical Role for Epigenome-Wide Studies
por: Singh, Rahul R., et al.
Publicado: (2019)

Nrf2 Mutation/Activation Is Dispensable for the Development of Chemically Induced Mouse HCC
por: Mattu, Sandra, et al.
Publicado: (2021)

Power and sample size estimation for epigenome-wide association scans to detect differential DNA methylation
por: Tsai, Pei-Chien, et al.
Publicado: (2015)

Revisiting the genome-wide significance threshold for common variant GWAS
por: Chen, Zhongsheng, et al.
Publicado: (2021)

Epigenome-Wide Association Study of Cognitive Functioning in Middle-Aged Monozygotic Twins
por: Starnawska, Anna, et al.
Publicado: (2017)

Epigenome-wide association study of plasma lipids in West Africans: the RODAM study
por: van der Linden, Eva L., et al.
Publicado: (2023)

Epigenome-Wide Association Studies (EWAS) in Cancer
por: Verma, Mukesh
Publicado: (2012)

EWASdb: epigenome-wide association study database
por: liu, Di, et al.
Publicado: (2019)

ELMOD3‐SH2D6 gene fusion as a possible co‐star actor in autism spectrum disorder scenario
por: Loi, Eleonora, et al.
Publicado: (2019)

Detecting multiple associations in genome-wide studies
por: Dudbridge, Frank, et al.
Publicado: (2006)

Epigenome-wide association study (EWAS) on lipids: the Rotterdam Study
por: Braun, Kim V. E., et al.
Publicado: (2017)

Are Genetic Risk Factors for Psychosis Also Associated with Dimension-Specific Psychotic Experiences in Adolescence?
por: Sieradzka, Dominika, et al.
Publicado: (2014)

Unbiased estimation of odds ratios: combining genomewide association scans with replication studies
por: Bowden, Jack, et al.
Publicado: (2009)

An epigenome-wide association study in whole blood of measures of adiposity among Ghanaians: the RODAM study
por: Meeks, Karlijn A.C., et al.
Publicado: (2017)

Advances in epigenome-wide association studies for common diseases
por: Paul, Dirk S., et al.
Publicado: (2014)

Epigenome-wide Association Studies and the Interpretation of Disease -Omics
por: Birney, Ewan, et al.
Publicado: (2016)

Epigenome-wide association study of leukocyte telomere length
por: Lee, Yunsung, et al.
Publicado: (2019)

Epigenome-wide association study of seizures in childhood and adolescence
por: Caramaschi, Doretta, et al.
Publicado: (2020)

Epigenome-wide association study on diffusing capacity of the lung
por: Terzikhan, Natalie, et al.
Publicado: (2021)

Colorectal cancer promoter methylation alteration affects the expression of glutamate ionotropic receptor AMPA type subunit 4 alternative isoforms potentially relevant in colon tissue
por: Vega-Benedetti, Ana Florencia, et al.
Publicado: (2021)

Editorial: Metabolism As a Therapeutic Target
por: Columbano, Amedeo, et al.
Publicado: (2017)

Epigenome-Wide Analysis of DNA Methylation in Parkinson’s Disease Cortex
por: Kaut, Oliver, et al.
Publicado: (2022)

pwrEWAS: a user-friendly tool for comprehensive power estimation for epigenome wide association studies (EWAS)
por: Graw, Stefan, et al.
Publicado: (2019)

An Efficient Approach to Screening Epigenome-Wide Data
por: Ray, Meredith A., et al.
Publicado: (2016)

Genome-wide epigenomic profiling for biomarker discovery
por: Dirks, René A. M., et al.
Publicado: (2016)

An epigenome-wide view of osteoarthritis in primary tissues
por: Kreitmaier, Peter, et al.
Publicado: (2022)

Epigenome-wide association study in healthy individuals identifies significant associations with DNA methylation and PBMC extract VEGF-A concentration
por: Gorenjak, Vesna, et al.
Publicado: (2020)

Accounting for cellular heterogeneity is critical in epigenome-wide association studies
por: Jaffe, Andrew E, et al.
Publicado: (2014)

Epigenome-wide association study of DNA methylation in panic disorder
por: Shimada-Sugimoto, Mihoko, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_87jhe404t1qjacaam1c36crn84