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Enzymatic synthesis of chiral amino‐alcohols by coupling transketolase and transaminase‐catalyzed reactions in a cascading continuous‐flow microreactor system
Rapid biocatalytic process development and intensification continues to be challenging with currently available methods. Chiral amino‐alcohols are of particular interest as they represent key industrial synthons for the production of complex molecules and optically pure pharmaceuticals. (2S,3R)‐2‐am...
Autores principales: | Gruber, Pia, Carvalho, Filipe, Marques, Marco P. C., O'Sullivan, Brian, Subrizi, Fabiana, Dobrijevic, Dragana, Ward, John, Hailes, Helen C., Fernandes, Pedro, Wohlgemuth, Roland, Baganz, Frank, Szita, Nicolas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813273/ https://www.ncbi.nlm.nih.gov/pubmed/28986983 http://dx.doi.org/10.1002/bit.26470 |
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