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Enzymatic synthesis of chiral amino‐alcohols by coupling transketolase and transaminase‐catalyzed reactions in a cascading continuous‐flow microreactor system

Rapid biocatalytic process development and intensification continues to be challenging with currently available methods. Chiral amino‐alcohols are of particular interest as they represent key industrial synthons for the production of complex molecules and optically pure pharmaceuticals. (2S,3R)‐2‐am...

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Detalles Bibliográficos
Autores principales: Gruber, Pia, Carvalho, Filipe, Marques, Marco P. C., O'Sullivan, Brian, Subrizi, Fabiana, Dobrijevic, Dragana, Ward, John, Hailes, Helen C., Fernandes, Pedro, Wohlgemuth, Roland, Baganz, Frank, Szita, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813273/
https://www.ncbi.nlm.nih.gov/pubmed/28986983
http://dx.doi.org/10.1002/bit.26470

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