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hPMSC transplantation restoring ovarian function in premature ovarian failure mice is associated with change of Th17/Tc17 and Th17/Treg cell ratios through the PI3K/Akt signal pathway

BACKGROUND: Human placenta-derived mesenchymal stem cell (hPMSC) transplantation has been demonstrated to be an effective way of recovering ovarian function in mice with autoimmune induced premature ovarian failure (POF). But the exact mechanism remains unclear. The goal of the present study is to i...

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Detalles Bibliográficos
Autores principales: Yin, Na, Wang, Yanlin, Lu, Xueyan, Liu, Ranran, Zhang, Lianshuang, Zhao, Wei, Yuan, Wendan, Luo, Qianqian, Wu, Hao, Luan, Xiying, Zhang, Hongqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813427/
https://www.ncbi.nlm.nih.gov/pubmed/29444704
http://dx.doi.org/10.1186/s13287-018-0772-x