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Amplification of PIP3 signalling by macropinocytic cups

In a role distinct from and perhaps more ancient than that in signal transduction, PIP3 and Ras help to spatially organize the actin cytoskeleton into macropinocytic cups. These large endocytic structures are extended by actin polymerization from the cell surface and have at their core an intense pa...

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Detalles Bibliográficos
Autores principales: Kay, Robert R., Williams, Thomas D., Paschke, Peggy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813501/
https://www.ncbi.nlm.nih.gov/pubmed/29444849
http://dx.doi.org/10.1042/BCJ20170785