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Amplification of PIP3 signalling by macropinocytic cups
In a role distinct from and perhaps more ancient than that in signal transduction, PIP3 and Ras help to spatially organize the actin cytoskeleton into macropinocytic cups. These large endocytic structures are extended by actin polymerization from the cell surface and have at their core an intense pa...
Autores principales: | Kay, Robert R., Williams, Thomas D., Paschke, Peggy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813501/ https://www.ncbi.nlm.nih.gov/pubmed/29444849 http://dx.doi.org/10.1042/BCJ20170785 |
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