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Mineralocorticoid hypertension and hypokalaemia induced by posaconazole

We describe severe hypokalaemia and hypertension due to a mineralocorticoid effect in a patient with myelodysplastic syndrome taking posaconazole as antifungal prophylaxis. Two distinct mechanisms due to posaconazole are identified: inhibition of 11β hydroxylase leading to the accumulation of the mi...

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Detalles Bibliográficos
Autores principales:	Boughton, Charlotte, Taylor, David, Ghataore, Lea, Taylor, Norman, Whitelaw, Benjamin C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bioscientifica Ltd 2018
Materias:	Unusual Effects of Medical Treatment
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813713/ https://www.ncbi.nlm.nih.gov/pubmed/29472988 http://dx.doi.org/10.1530/EDM-17-0157

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