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Paternal lineage early onset hereditary ovarian cancers: A Familial Ovarian Cancer Registry study

Given prior evidence that an affected woman conveys a higher risk of ovarian cancer to her sister than to her mother, we hypothesized that there exists an X-linked variant evidenced by transmission to a woman from her paternal grandmother via her father. We ascertained 3,499 grandmother/granddaughte...

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Detalles Bibliográficos
Autores principales: Eng, Kevin H., Szender, J. Brian, Etter, John Lewis, Kaur, Jasmine, Poblete, Samantha, Huang, Ruea-Yea, Zhu, Qianqian, Grzesik, Katherine A., Battaglia, Sebastiano, Cannioto, Rikki, Krolewski, John J., Zsiros, Emese, Frederick, Peter J., Lele, Shashikant B., Moysich, Kirsten B., Odunsi, Kunle O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813894/
https://www.ncbi.nlm.nih.gov/pubmed/29447163
http://dx.doi.org/10.1371/journal.pgen.1007194